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Evidence is increasing that addiction without exception is related to difficulty with the brain's reward center, specially the mesolimbic system. This area of the problem regulates reward responses in acquiring food and sex, as well as in nurturing infants and children. One of the most important neurotransmitters linked to reward responses, both whenever they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the volume of dopamine released in responding to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to shed weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err on the side of caution and allow FDA do its job and demand some research be done so your public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on his or her medications.

Researchers discovered that participants taking this drug for any year, lost weight within one month and have kept the weight off throughout the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them more potent and safer.

Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and for that reason it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that at the time of right now there are no long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug can also raise hypertension and heartrate, and must not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

To keep up with probably the most current articles from Wendi, the Indiana Addiction Recovery Examiner, click the subscribe link towards the top of the page to obtain email notification when new content is published. Please leave a comment for any article.


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